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KMID : 0984920150170010017
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Journal of Skin Barrier Research
2015 Volume.17 No. 1 p.17 ~ p.19
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Applications of Metabolomics in Bioactive Natural Compound Discovery and Development
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Kim Kyoung-Jin
Kim Yun-Gon
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Abstract
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Mass spectrometry is a powerful tool for discovering novel disease biomarkers and biologically active compounds from complex mixtures such as natural product extracts. Here, we provide examples of the development and use of mass spectrometry-based approaches (i.e., proteomics, glycomics, lipidomics, peptidomics) to elucidate protein-glycan interactions, endogenous lipids regulating adipogenesis, and proteolytic pathway of bioactive peptides.
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KEYWORD
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Mass spectrometry, Biomarker, Metabolomics, Natural compounds
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Listed journal information
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